Shi Group

 

 

 



Waterfall

A secluded waterfall off of "The Loch" trail in Rocky Mountain National Park (August 2007)
 

 

Publications

 

162.    Bing Xu, Guang Li, Jing Li, &Yian Shi.  “Total Synthesis of the Proposed Structure of Marineosin A”, Org. Lett. 2016, 18, 2028-2031. Click here to see article.

 

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161.    Hongjie Pan, Hu Huang, Weigang Liu, Hua Tian, &Yian Shi.  “Phosphine Oxide-Sc(OTf)3 Catalyzed Highly Regio- and Enantioselective Bromoaminocyclization of (E)-Cinnamyl Tosylcarbamates.  An Approach to a Class of Synthetically Versatile Functionalized Molecules”, Org. Lett. 2016, 18, 896-899. Click here to see article.

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160.    Wenju Chang, Jingfu Li, Wenlong Ren, &Yian Shi.  “Pd-Catalyzed Regioselective Hydroesterification of 2-Allylphenols to Seven-Membered Lactones without External CO Gas”, Org. Biomol. Chem. 2016, 14, 3047-3052. Click here to see article.

 

Graphical abstract: Pd-Catalyzed regioselective hydroesterification of 2-allylphenols to seven-membered lactones without external CO gas

 

159.    Chao Rong, Hongjie Pan, Mao Liu, Hua Tian, &Yian Shi.  “A Facile Approach to Optically Active Hydroquinoline-2-carboxylates by One-Pot Asymmetric Michael/Transamination/Cyclization Process”, Chem. Eur. J. 2016, 22, 2887-2891. Click here to see article.

 

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158.    Zequan Li &Yian Shi.  “Chiral Phosphine Oxide-Sc(OTf)3 Complex Catalyzed Enantioselective Bromoaminocyclization of 2-Benzofuranylmethyl N-Tosylcarbamates.  Approach to a Novel Class of Optically Active Spiro Compounds”, Org. Lett. 2015, 17, 5752-5755. Click here to see article.

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157.    Yazhou Wang, Wei Liu, Wenlong Ren, &Yian Shi.  “Synthesis and Evaluation of 5,5’-Bitetralone-Based Chiral Phosphoric Acids”, Org. Lett. 2015, 17, 4976-4979. Click here to see article.

 

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156.    Jingfu Li, Wenju Chang, Wenlong Ren, Wei Liu, Haining Wang, &Yian Shi.  “A Palladium-Catalyzed Enantioselective Hydroesterification of Alkenylphenols with Phenyl Formate.  A Facile Approach to Optically Active Dihydrocoumarins”, Org. Biomol. Chem. 2015, 13, 10341-10347. Click here to see article.

 

Graphical abstract: A palladium-catalyzed enantioselective hydroesterification of alkenylphenols with phenyl formate. A facile approach to optically active dihydrocoumarins

 

155.    Weigang Liu, Hongjie Pan, Hua Tian, &Yian Shi.  “Enantioselective 6-exo Bromoaminocyclization of Homoallylic N-Tosylcarbamates Catalyzed by a Novel Monophosphine-Sc(OTf)3 Complex”, Org. Lett. 2015, 17, 3956-3959. Click here to see article.

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154.    Jie Dai, Wenlong Ren, Haining Wang, &Yian Shi.  -Amino Acid Derivatives“A Facile Approach to  via Palladium-Catalyzed Hydrocarboxylation of Enimides with Formic Acid”, Org. Biomol. Chem. 2015, 13, 8429-8432. Click here to see article.

 

Graphical abstract: A facile approach to β-amino acid derivatives via palladium-catalyzed hydrocarboxylation of enimides with formic acid

 

153.    Yang Wang, Wenlong Ren, &Yian Shi.  “An Atom-economic Approach to Carboxylic Acids via Pd-Catalyzed Direct Addition of Formic Acid to Olefins with Acetic Anhydride as a Co-catalyst”, Org. Biomol. Chem. 2015, 13, 8416-8419. Click here to see article.

 

Graphical abstract: An atom-economic approach to carboxylic acids via Pd-catalyzed direct addition of formic acid to olefins with acetic anhydride as a co-catalyst

 

152.    Xun Zhang, Jing Li, Hua Tian, &Yian Shi.  “Catalytic Asymmetric Bromination of Unfunctionalized Olefins with H2O as a Nucleophile”, Chem. Eur. J. 2015, 21, 11658-11663. Click here to see article.

 

 

151.    Wenlong Ren, Wenju Chang, Yang Wang, Jingfu Li, &Yian Shi.  “Pd-Catalyzed Regiodivergent Hydroesterification of Aryl Olefins with Phenyl Formate”, Org. Lett. 2015, 17, 3544-3547. Click here to see article.

 

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150.    Hu Huang, Hongjie Pan, Yudong Cai, Mao Liu, Hua Tian, &Yian Shi. “Enantioselective 6-endo Bromoaminocyclization of 2,4-Dienyl N-Tosylcarbamates Catalyzed by a Chiral Phosphine Oxide-Sc(OTf)3 Complex. A Dramatic Additive Effect”, Org. Biomol. Chem. 2015, 13, 3566-3570. Click here to see article.

Graphical abstract: Enantioselective 6-endo bromoaminocyclization of 2,4-dienyl N-tosylcarbamates catalyzed by a chiral phosphine oxide-Sc(OTf)3 complex. A dramatic additive effect

 

149.    Ying Xie, Hongjie Pan, Mao Liu, Xiao Xiao, &Yian Shi.  “Progress in Asymmetric Biomimetic Transamination of Carbonyl Compounds”, Chem. Soc. Rev. 2015, 44, 1740-1748. Click here to see article.

Graphical abstract: Progress in asymmetric biomimetic transamination of carbonyl compounds

 

148.    Yang Wang, Wenlong Ren, Jingfu Li, Haining Wang, &Yian Shi.  “Facile Palladium-Catalyzed Hydrocarboxylation of Olefins without External CO Gas”, Org. Lett. 2014, 16, 5960-5963. Click here to see article.

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147.    Jing Li, Mao Liu, Qi Li, Hua Tian, &Yian Shi.  “A Facile Approach to Spirocyclic 2-Azido Indolines via Azidation of Indoles with Ceric Ammonium Nitrate”, Org. Biomol. Chem. 2014, 12, 9769-9772. Click here to see article.

Graphical abstract: A facile approach to spirocyclic 2-azido indolines via azidation of indoles with ceric ammonium nitrate

 

146.    Mao Liu, Ying Xie, Jing Li, Hongjie Pan, Hua Tian, &Yian Shi.  “Synthesis of Optically Active Deuterated Primary Amines via Reduction of N-tert-Butanesulfinyl Aldimines”, J. Org. Chem. 2014, 79, 8417-8421. Click here to see article.

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145.    Lijun Li, Cunxiang Su, Xiaoqin Liu, Hua Tian, &Yian Shi.  “Catalytic Asymmetric Intermolecular Bromoesterification of Unfunctionalized Olefins”, Org. Lett. 2014, 16, 3728-3731. Click here to see article.

 

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144.    Cunxiang Su, Ying Xie, Hongjie Pan, Mao Liu, Hua Tian, &Yian Shi.  “Organocatalytic Synthesis of Optically -Amino Esters via Asymmetric Biomimetic Transamination”,-Branched Active  Org. Biomol. Chem. 2014, 12, 5856-5860. Click here to see article.

Graphical abstract: Organocatalytic synthesis of optically active β-branched α-amino esters via asymmetric biomimetic transamination

 

143.    Hongjie Pan, Ying Xie, Mao Liu, &Yian Shi.  “Organocatalytic Asymmetric Biomimetic Transamination of Keto Acetals to Chiral Amino Acetals”, RSC Adv. 2014, 4, 2389-2392. Click here to see article.

 

Graphical abstract: Organocatalytic asymmetric biomimetic transamination of α-keto acetals to chiral α-amino acetals

 

142.    Haining Wang, Ben Dong, Yang Wang, Jingfu Li, &Yian Shi.  “A Palladium-Catalyzed Regioselective Hydroesterification of Alkenylphenols to Lactones with Phenyl Formate as CO Source”, Org. Lett. 2014, 16, 186-189. Click here to see article.

 

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141.    Yingguang Zhu, Richard G. Cornwall, Haifeng Du, Baoguo Zhao, & Yian Shi. “Catalytic Diamination of Olefins via N−N Bond Activation”, Acc. Chem. Res. 2014, 47, 3665−3678. Click here to see article.

 

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140.    Yingguang Zhu, Tao Xiong, Wenyong Han, & Yian Shi. “Copper-Catalyzed Oxidative Homo- and Cross-Coupling of Grignard Reagents Using Diaziridinone”, Org. Lett. 2014, 16, 6144−6147. Click here to see article.

 

 

139.    Yingguang Zhu & Yian Shi. “Cu(I)-Catalyzed Sequential Diamination and Dehydrogenation of Terminal Olefins: A Facile Approach to Imidazolinones”, Chem. Eur. J. 2014, 20, 13901–13904. Click here to see article.

 

 

138.    Huaiji Zheng, Yingguang Zhu, & Yian Shi. “Palladium(0)-Catalyzed Heck Reaction/CH Activation/Amination Sequence with Diaziridinone: A Facile Approach to Indolines”, Angew. Chem. Int. Ed. 2014, 53, 11280–11284. Click here to see article.

 

 

137.    Yingguang Zhu, Qian Wang, Richard G. Cornwall, & Yian Shi. “Organocatalytic Asymmetric Epoxidation and Aziridination of Olefins and Their Synthetic Applications”, Chem. Rev. 2014, 114, 8199−8256. Click here to see article.

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136.    Yingguang Zhu & Yian Shi. “A Facile Copper(I)-Catalyzed Homocoupling of Terminal Alkynes to 1,3-Diynes with Diaziridinone under Mild Conditions”, Org. Biomol. Chem. 2013, 11, 7451-7454.  Click here to see article.

 

Graphical abstract: A facile copper(i)-catalyzed homocoupling of terminal alkynes to 1,3-diynes with diaziridinone under mild conditions

 

135.    Thomas A. Ramirez, Qian Wang, Yingguang Zhu, Huaiji Zheng, Xingao Peng, Richard G. Cornwall, & Yian Shi. “Pd(0)-Catalyzed Sequential C-N Bond Formation via Allylic and Aromatic C-H Amination of α-Methylstyrenes with Diaziridinone”, Org. Lett. 2013, 15, 4210-4213. Click here to see article.

 

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134.    Yingguang Zhu & Yian Shi. “Facile Cu(I)-Catalyzed Oxidative Coupling of Anilines to Azo Compounds and Hydrazines with Diaziridinone under Mild Conditions”, Org. Lett. 2013, 15, 1942-1945.  Click here to see article.

 

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133.    Yingguang Zhu, Baoguo Zhao, & Yian Shi. “Highly Efficient Cu(I)-Catalyzed Oxidation of Alcohols to Ketones and Aldehydes with Diaziridinone”, Org. Lett. 2013, 15, 992-995. Click here to see article.

 

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132.    Richard G. Cornwall, Baoguo Zhao, & Yian Shi. “Catalytic Asymmetric Synthesis of Cyclic Sulfamides from Conjugated Dienes”, Org. Lett. 2013, 15, 796-799. Click here to see article.

 

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131.    O. Andrea Wong, Brian Nettles, &Yian Shi.  “Oxidations”, Carbohydrates – Tools for Stereoselective Synthesis, Boysen, M.M.K. Ed., WILEY-VCH, Germany, 2013, pp 321-350. Click here to see article.

 

 

130.    Deshun Huang, Xiaoqin Liu, Lijun Li, Yudong Cai, Weigang Liu, &Yian Shi.  “Enantioselective Bromoaminocyclization of Allyl N-Tosylcarbamates Catalyzed by a Chiral Phosphine-Sc(OTf)3 Complex”, J. Am. Chem. Soc. 2013, 135, 8101-8104. Click here to see article.

 

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129.    Donghao Cheng, Deshun Huang, &Yian Shi.  “Synergistic Effect of Additives on Cyclopropanation of Olefins”, Org. Biomol. Chem. 2013, 11, 5588-5591. Click here to see article.

 

Graphical abstract: Synergistic effect of additives on cyclopropanation of olefins

 

128.    Guang Li, Xun Zhang, Qi Li, Pengju Feng, &Yian Shi.  “A Concise Approach to the Spiroiminal Fragment of Marineosins”, Org. Biomol. Chem. 2013, 11, 2936-2938. Click here to see article.

 

Graphical abstract: A concise approach to the spiroiminal fragment of marineosins

 

127.    Lijun Li, Zequan Li, Deshun Huang, Haining Wang, &Yian Shi.  “Chiral Phosphoric Acid Catalyzed Enantioselective Sulfamination of Amino-alkenes”, RSC Adv. 2013, 3, 4523-4525. Click here to see article.

Graphical abstract: Chiral phosphoric acid catalyzed enantioselective sulfamination of amino-alkenes

 

126.    Yudong Cai &Yian Shi.  “Synthesis and X-ray Characterization of Novel Palladium(II) Complexes with Tunable Chiral Anionic Counterions”, Dalton Trans.2013, 42, 5232-5236. Click here to see article.

 

Graphical abstract: Synthesis and X-ray characterization of novel palladium(ii) complexes with tunable chiral anionic counterions

 

125.    Qi Li, Guang Li, Shaobo Ma, Pengju Feng, &Yian Shi.  “An Approach to the Skeleton of Aspidophylline A”, Org. Lett. 2013, 15, 2601-2603. Click here to see article.

 

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124.    Mao Liu, Jing Li, Xiao Xiao, Ying Xie, &Yian Shi.  “An Efficient Synthesis of Optically Active Trifluoromethyl Aldimines via Asymmetric Biomimetic Transamination”, Chem. Commun. 2013, 49, 1404-1406. Click here to see article.

Graphical abstract: An efficient synthesis of optically active trifluoromethyl aldimines via asymmetric biomimetic transamination

 

123.    Richard G. Cornwall, O. Andrea Wang, Haifeng Du, Thomas A. Ramirez, & Yian Shi. “A Novel Class of Tunable Cyclopropanation Reagents (RXZnCH2Y) and Their Synthetic Applications”, Org. Biomol. Chem. 2012, 10, 5498-5513. Click here to see article.

 

Graphical abstract: A novel class of tunable cyclopropanation reagents (RXZnCH2Y) and their synthetic applications

 

122.    Thomas A Ramirez, O. Andrea Wang, & Yian Shi.  Discussion Addendum for: Synthesis of 1,2:4,5-Di-o-isopropylidene–D-erythro-2,3-hexodiulo-2,6-pyranose.  A Highly Enantioselective Ketone Catalyst for Epoxidation/Asymmetric Epoxidation of trans-β-Methylstyrene and 1-Phenylcyclohexene using a D-Fructose-derived Ketone:  (R,R)-trans-β–Methylstyrene Oxide and (R,R)-1-Phenylcyclohexene Oxide”, Org. Synth. 2012, 89, 350-373. Click here to see article.

 

121.    O. Andrea Wong, Thomas A. Ramirez, &Yian Shi.  “Organocatalyzed Asymmetric Epoxidation of Alkenes”, Comprehensive Chirality, Carreira, E. M. and Yamamoto, H. Ed., Elsevier Ltd., 2012, Vol. 6, pp 528-553.   Click here to see article.

 

120.    Thomas A Ramirez & Yian Shi.  “Spiro[6H-1,3-dioxolo[4,5-c]pyran-6,5’-oxazolidine]-3’-carboxylic acid, tetrahydro-2,2-dimethyl-2’,7-dioxo-,2-methyl-2-propyl ester, (3aR, 5’S, 7aR)-”, Electronic Encyclopedia of Reagents for Organic Synthesis, 2012.  Click here to see article.

 

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119.    O. Andrea Wang, Thomas A. Ramirez, & Yian Shi.  "Asymmetric Ketone and Iminium Salt-Catalyzed Epoxidations", Science of Synthesis, List, B. Ed., Georg Thieme Verlag KG, Stuttgart, Germany, 2012, pp 783-830. 

 

118.    Thomas A. Ramirez, Baoguo Zhao, & Yian Shi.  “Recent Advances in Transition Metal-Catalyzed sp3 C-H Amination Adjacent to Double Bonds and Carbonyl Groups”, Chem. Soc. Rev. 2012, 41, 931-942. Click here to see article.

Graphical abstract: Recent advances in transition metal-catalyzed sp3 C–H amination adjacent to double bonds and carbonyl groups

 

117.    Ying Xie, Hongjie Pan, Xiao Xiao, Songlei Li, &Yian Shi.  “Organocatalytic Asymmetric Biomimetic Transamination of Aromatic Ketone to Optically Active Amine”, Org. Biomol. Chem. 2012, 10, 8960-8962. Click here to see article.

Graphical abstract: Organocatalytic asymmetric biomimetic transamination of aromatic ketone to optically active amine

 

116.    Xiao Xiao, Mao Liu, Chao Rong, Fazhen, Xue, Songlei Li, Ying Xie, &Yian Shi.  “An Efficient Asymmetric Biomimetic Transamination of Keto Esters to Chiral-Amino Esters”, Org. Lett. 2012, 14, 5270-5273. Click here to see article.

 

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115.    Lijun Li, Haining Wang, Deshun Huang, &Yian Shi.  “Acid-Catalyzed Regioselective Sulfamination of Amino Alkenes and Stereoselective Rearrangement of Pyrrolidines to Piperidines”, Tetrahedron 2012, 68, 9853-9859. Click here to see article.

 

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114.    Song Chen, Chao Rong, Pengju Feng, Songlei Li, &Yian Shi.  “Stereoselective Construction of the Tetracyclic Core of Cryptotrione”, Org. Biomol. Chem. 2012, 10, 5518-5520. Click here to see article.

 

Graphical abstract: Stereoselective construction of the tetracyclic core of Cryptotrione

 

113.    Fazhen Xue, Xiao Xiao, Haining Wang, &Yian Shi.  “The Effect of Benzyl Amine on the Efficiency of the Base-Catalyzed Transamination of Keto Esters”, Tetrahedron 2012, 68, 6862-6867. Click here to see article.

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112.    Huan Guan, Haining Wang, Deshun Huang, &Yian Shi. “Enantioselective Oxysulfenylation and Oxyselenenylation of Olefins Catalyzed by Chiral Brønsted Acids”, Tetrahedron 2012, 68, 2728-2735. Click here to see article.

 

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111.    Xianyou Peng, Peijun Li, &Yian Shi.  “Synthesis of (+)-Ambrisentan via Chiral Ketone-Catalyzed Asymmetric Epoxidation”, J. Org. Chem. 2012, 77, 701-703. Click here to see article.

 

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110.    Deshun Huang, Haining Wang, Fazhen Xue, Huan Guan, Lijun Li, Xianyou Peng, &Yian Shi.  “Enantioselective Bromocyclization of Olefins Catalyzed by Chiral Phosphoric Acid”, Org. Lett. 2011, 13, 6350-6353. Click here to see article.

 

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109.    Pengju Feng, Yukai Fan, Fazhen Xue, Weigang Liu, Songlei Li, &Yian Shi.  “An Approach to the Hexacyclic Skeleton of Trigonoliimines”, Org. Lett. 2011, 13, 5827-5829. Click here to see article.

 

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108.    Xiao Xiao, Ying Xie, Cunxiang Su, Mao Liu, &Yian Shi.  “Organocatalytic Asymmetric Biomimetic Transamination:  From a-Keto Esters to Optically Active a-Amino Acid Derivatives”, J. Am. Chem. Soc. 2011, 133, 12914-12917. Click here to see article.

 

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107.    Deshun Huang, Haining Wang, Fazhen Xue, &Yian Shi.  “FeCl3/NaI-Catalyzed Allylic C-H Oxidation of Arylalkenes with a Catalytic Amount of Disulfide under Air”, J. Org. Chem.2011, 76, 7269-7274. Click here to see article.

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106.    Yukai Fan, Pengju Feng, Mao Liu, Hongjie Pan, &Yian Shi.  “A Concise Approach to the Dalesconol Skeleton”, Org. Lett. 2011, 13, 4494-4497. Click here to see article.

 

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105.    Haining Wang, Deshun Huang, Donghao Cheng, Lijun Li, &Yian Shi.  “Acid-Catalyzed Regioselective Sulfetherification of Alkenols and Stereoselective Rearrangement of Tetrahydrofuran to Tetrahydropyran”, Org. Lett. 2011, 13, 1650-1653. Click here to see article.

 

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104.Deshun Huang, Haining Wang, Huan Guan, Hu Huang, &Yian Shi.  “An Acid-Catalyzed Formal Allylic C-H Oxidation of Aryl Cycloalkenes with N-Propylthiosuccinimide”, Org. Lett. 2011, 13, 1548-1551. Click here to see article.

 

103.Baoguo Zhao, Xingao Peng, Yingguang Zhu, Thomas A. Ramirez, Richard G. Cornwall, & Yian Shi.  “Cu(I)-Catalyzed Diamination of Conjugated Dienes.  Complementary Regioselectivity from Two Distinct Mechanistic Pathways Involving Cu(II) and Cu(III) Species”, J. Am. Chem. Soc. 2011, 133, 20890-20900. Click here to see article.

 

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102.Xingao Peng, Yingguang Zhu, Thomas A. Ramirez, Baoguo Zhao, & Yian Shi.  “New Reactivity of Oxaziridine:  Pd(II)-Catalyzed Aromatic C-H Ethoxycarbonylation via C-C Bond Cleavage”, Org. Lett. 2011, 13, 5244-5247. Click here to see article.

 

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101.Richard G. Cornwall, Baoguo Zhao, & Yian Shi.  “Complementary Regioselectivity in the Cu(I)-Catalyzed Diamination of Conjugated Dienes to Form Cyclic Sulfamides”, Org. Lett. 2011, 13, 434-437. Click here to see article.

 

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100.Baoguo Zhao, Xingao Peng, Sunliang Cui, & Yian Shi.  “Cu(I)-Catalyzed Regioselective Diamination of Conjugated Dienes via Dual Mechanistic Pathways”, J. Am. Chem. Soc. 2010, 132, 11009-11011. Click here to see article.

 

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99.  Baoguo Zhao, Haifeng Du, Sunliang Cui, & Yian Shi.  “Synthetic and Mechanistic Studies on Pd(0)-Catalyzed Diamination of Conjugated Dienes”, J. Am. Chem. Soc. 2010, 132, 3523-3532. Click here to see article.

 

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98.  Thomas A. Ramirez, Baoguo Zhao, & Yian Shi.  “An Effective C-C Double Bond Formation via Cu(I)-Catalyzed Dehydrogenation”, Tetrahedron Lett. 2010, 51, 1822-1825. Click here to see article.

 

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97.  Baoguo Zhao, Haifeng Du, Renzhong Fu, & Yian Shi.  “Pd(0)-Catalyzed Asymmetric Allylic and Homoallylic Diamination of 4-Phenyl-1-butene with Di-tert-butyldiaziridinone”, Org. Synth. 2010, 87, 263-274. Click here to see article.

 

96.  O. Andrea Wong & Yian Shi.  “Chiral Ketone and Iminium Catalysts for Olefin Epoxidation”, Topics in Current Chemistry; List, B. Ed.; Springer: New York, 2010; Vol 291. pp 201-232.

 

 

95. Yian Shi.  "Organocatalytic Oxidation.  Ketone-catalyzed Asymmetric Epoxidation of Olefins and Synthetic Applications", Modern Oxidation Methods (Second Edition), Backvall, J.E. Ed., WILEY-VCH, Germany, 2010, pp 85-115.

 

94.  Jiang Long, Liang Xu, Haifeng Du, Kai Li, & Yian Shi.  “Mechanistic Studies on a Dipeptide-Promoted Asymmetric Cyclopropanation of Unfunctionalized Olefins”, Org. Lett. 2009, 11, 5226-5229. Click here to see article.

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93.  Baoguo Zhao, Haifeng Du, & Yian Shi.  “Cu(I)-Catalyzed Diamination of Conjugated Olefins with Tunable Anionic Counterions.  A Possible Approach to Asymmetric Diamination”, J. Org. Chem. 2009, 74, 8392-8395. Click here to see article.

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92.  Haifeng Du, Baoguo Zhao, & Yian Shi.  “Pd(0)-Catalyzed Diamination of trans-1-Phenyl-1,3-butadiene with Di-tert-butyldiaziridinone as Nitrogen Source”, Org. Synth. 2009, 86, 315. Click here to see article.

91.   Christopher P. Burke & Yian Shi.  “Enantioselective Epoxidation of Nonconjugated cis-Olefins by Chiral Dioxirane”, Org. Lett. 2009, 11, 5150-5153. Click here to see article.

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90.   O. Andrea Wong & Yian Shi.  “Asymmetric Epoxidation of Fluoroolefins by Chiral Dioxirane.  Fluorine Effect on Enantioselectivity”, J. Org. Chem. 2009, 74, 8377-8380. Click here to see article.

 

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89.   Renzhong Fu, Baoguo Zhao, & Yian Shi.  “Synthesis of (+)-CP-99,994 via Pd(0)-Catalyzed Asymmetric Allylic and Homoallylic C-H Diamination of Terminal Olefin”, J. Org. Chem. 2009, 74, 7577-7580. Click here to see article.

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88.  O. Andrea Wong, Bin Wang, Mei-Xin Zhao, & Yian Shi.  “Asymmetric Epoxidation Catalyzed by α,α-Dimethylmorpholinone Ketone.  Methyl Group Effect on Spiro and Planar Transition States”, J. Org. Chem. 2009, 74, 6335-6338. Click here to see article.

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87.  Yuehong Wen, Baoguo Zhao, & Yian Shi.  “Cu(I)-Catalyzed Diamination of Disubstituted Terminal Olefins:  An Approach to Potent NK1 Antagonist”, Org. Lett. 2009, 11, 2365-2368. Click here to see article.

 

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86.  Baoguo Zhao, Haifeng Du, & Yian Shi.  “Cu(I)-Catalyzed C-H α-Amination of Aryl Ketones:  Direct Synthesis of Imidazolinones”, J. Org. Chem. 2009, 74, 4411-4413. Click here to see article.

 

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85.  Bin Wang, Xin-Yan Wu, O. Andrea Wong, Brian Nettles, Mei-Xin Zhao, Dajun Chen, & Yian Shi.  “A Diacetate Ketone-Catalyzed Asymmetric Epoxidation of Olefins”, J. Org. Chem. 2009, 74, 3986-3989. Click here to see article.

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84. Bin Wang & Yian Shi.  "Three-membered Cyclic Peroxides", Science of Synthesis, Vol. 38, Berkessel, A. Ed., Georg Thieme Verlag KG, Stuttgart, Germany, 2009, pp 275-322.

 

83.  Bin Wang, O. Andrea Wong, Mei-Xin Zhao, & Yian Shi.  “Asymmetric Epoxidation of 1,1-Disubstituted Terminal Olefins by Chiral Dioxirane via a Planar-like Transition State”, J. Org. Chem. 2008, 73, 9539-9543. Click here to see article.

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82.  Bin Wang, Haifeng Du, & Yian Shi.  “A Palladium-Catalyzed Dehydrogenative Diamination of Terminal Olefins”, Angew. Chem. Int. Ed. 2008, 47, 8224-8227. Click here to see article.

 

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81.  Haifeng Du, Baoguo Zhao, Weicheng Yuan, & Yian Shi.  “Cu(I)-Catalyzed Asymmetric Diamination of Conjugated Dienes”, Org. Lett. 2008, 10, 4231-4234. Click here to see article.

 

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80.  O. Andrea Wong & Yian Shi.  “1,2:4,5-Di-O-isopropylidene-β-D-erythro-hexo-2,3-diluo-2,6-pyranose”, Electronic Encyclopedia of Reagents for Organic Synthesis 2008. Click here to see article.

 

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79.  O. Andrea Wong & Yian Shi.  “Organocatalytic Oxidation.  Asymmetric Epoxidation of Olefins Catalyzed by Chiral Ketones and Iminium Salts”, Chem Rev. 2008, 3958-3987. Click here to see article.

 

78.  Haifeng Du, Baoguo Zhao, & Yian Shi.  “Catalytic Asymmetric Allylic and Homoallylic Diamination of Terminal Olefins via Formal C-H Activation”, J. Am. Chem. Soc. 2008, 130, 8590-8591. Click here to see article.

 

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77.  Baoguo Zhao, Haifeng Du, & Yian Shi.  “A Cu(I)-Catalyzed C-H α-Amination of Esters.  Direct Synthesis of Hydantoins”, J. Am. Chem. Soc. 2008, 130, 7220-7221. Click here to see article.

 

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76.  David Goeddel & Yian Shi.  "Synthesis of Epoxides from Alkenes with Organic Oxidants", Science of Synthesis, Vol. 37, Forsyth, C.J. Ed., Georg Thieme Verlag KG, Stuttgart, Germany, 2008, pp 277-320.

 

75.  Baoguo Zhao, Haifeng Du, & Yian Shi.  “Cu(I)-Catalyzed Cycloguanidination of Olefins”, Org. Lett. 2008, 10, 1087-1090. Click here to see article.

 

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74.  Liang Xu & Yian Shi.  “Chiral N-Heterocyclic Carbene-Pd(0)-Catalyzed Asymmetric Diamination of Conjugated Dienes and Triene”, J. Org. Chem. 2008, 73, 749-751. Click here to see article.

 

Figure

 

73.  Baoguo Zhao, Weicheng Yuan, Haifeng Du, & Yian Shi.  “Cu(I)-Catalyzed Intermolecular Diamination of Activated Terminal Olefins”, Org. Lett. 2007, 9, 4943-4945. Click here to see article.

 

Figure

 

72.  Haifeng Du, Weicheng Yuan, Baoguo Zhao, & Yian Shi. “Catalytic Asymmetric Diamination of Conjugated Dienes and Triene”, J. Am. Chem. Soc. 2007, 129, 11688-11689Click here to see article.

 

Figure

 

71. Liang Xu, Haifeng Du, & Yian Shi. “Diamination of Conjugated Dienes and Trienes Catalyzed by N-Heterocyclic Carbene-Pd(0) Complexes”, J. Org. Chem. 2007, 72, 7038-7041Click here to see article.

 

Figure

 

70. Christopher P. Burke, Lianhe Shu, & Yian Shi. “An N-Aryl-Substituted Oxazolidinone-Containing Ketone-Catalyzed Asymmetric Epoxidation with Hydrogen Peroxide as the Primary Oxidant”, J. Org. Chem. 2007, 72, 6320-6323Click here to see article.

 

Figure

 

69. Weicheng Yuan, Haifeng Du, Baoguo Zhao, & Yian Shi. “A Mild Cu(I)-Catalyzed Regioselective Diamination of Conjugated Dienes”, Org. Lett. 2007, 9, 2589-2591Click here to see article.

 

Figure

 

68.  Haifeng Du, Weicheng Yuan, Baoguo Zhao, & Yian Shi. “A Pd(0)-Catalyzed Diamination of Terminal Olefins at Allylic and Homoallylic Carbons via Formal C-H Activation under Solvent-Free Conditions”, J. Am. Chem. Soc. 2007, 129, 7496-7497Click here to see article.

 

Figure

 

67.  Christopher P. Burke & Yian Shi. “Enantioselective Epoxidation of Conjugated cis-Enynes by Chiral Dioxirane”, J. Org. Chem. 2007, 72, 4093-4097Click here to see article.

 

Figure

 

66.  Haifeng Du, Baoguo Zhao, & Yian Shi. “A Facile Pd(0)-Catalyzed Regio- and Stereoselective Diamination of Conjugated Dienes and Trienes”, J. Am. Chem. Soc. 2007, 129, 762-763Click here to see article.

 

Figure

 

65.  David Goeddel & Yian Shi.  "An Oxazolidinone Ketone Catalyst for the Asymmetric Epoxidation of cis-Olefins", Catalysts for Fine Chemical Synthesis:  Regio- and Stereo- Controlled Oxidations and Reduction”, Roberts, S.M. and Whittall, J. Eds., John Wiley & Sons, Ltd, West Sussex, England, 2007, pp 215-224.

 

64.  Yu-Mei Shen, Mei-Xin Zhao, Jiaxi Xu, & Yian Shi.  “An Amine-Promoted Aziridination of Chalcones”, Angew. Chem. Int. Ed. 2006, 45, 8005-8008Click here to see article.

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63.  Bin Wang, Yu-Mei Shen, & Yian Shi.  “Enantioselective Synthesis of γ-Aryl-γ-butyrolactones by Sequential Asymmetric Epoxidation, Ring Expansion, and Baeyer-Villiger Oxidation”, J. Org. Chem. 2006, 71, 9519-9521Click here to see article.

Figure

 

62. Mei-Xin Zhao, David Goeddel, Kai Li, & Yian Shi. “A Practical Synthesis of N-Aryl-Substituted Oxazolidinone-Containning Ketone Catalysts for Asymmetric Epoxidation”, Tetrahedron 2006, 62, 8064-8068. Click here to see article.

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61.  Yu-Mei Shen, Bin Wang, & Yian Shi. “Enantioselective Synthesis of 2-Alkyl-2-Aryl Cyclopentanones by Asymmetric Epoxidation of Tetrasubstituted Cyclobutylidene Olefins and Epoxide Rearrangement”, Tetrehedron Lett. 2006, 47, 5455-5458. Click here to see article.

 

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60.  Haifeng Du, Jiang Long, & Yian Shi. “Catalytic Asymmetric Simmons-Smith Cyclopropanation of Silyl Enol Ethers. Efficient Synthesis of Optically Active Cyclopropanol Derivatives”, Org. Lett. 2006, 8, 2827-2829. Click here to see article.

 

Figure

 

59.  Mei-Xin Zhao, & Yian Shi. “Practical Synthesis of an L-Fructose-Derived Ketone Catalyst for Asymmetric Epoxidation of Olefins”, J. Org. Chem. 2006, 71, 5377-5379. Click here to see article.

 

Figure

 

58.  Christopher P. Burke, & Yian Shi. “Regio- and Enantioselective Epoxidation of Dienes by a Chiral Dioxirane: Synthesis of Optically Active Vinyl cis-Epoxides”, Angew. Chem. Int. Ed. 2006, 45, 4475-4478. Click here to see article.

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57.  Andrea O. Wong, & Yian Shi. “Studies of Substituent Effect on Asymmetric Epoxidation of Chromenes by Chiral Dioxirane”, J. Org. Chem. 2006, 71, 3973-3976. Click here to see article.

 

Figure

 

56.  Yu-Mei Shen, Bin Wang, & Yian Shi. “Enantioselective Synthesis of 2-Aryl Cyclopentanones by Asymmetric Epoxidation and Epoxide Rearrangement”, Angew. Chem. Int. Ed. 2006, 45, 1429-1432. Click here to see article.

Thumbnail image of graphical abstract

 

55.  David Goeddel, Lianhe Shu, Yi Yuan, Andrea O. Wong, Bin, Wang, & Yian Shi. “Effective Asymmetric Epoxidation of Styrenes by Chiral Dioxirane”, J. Org. Chem. 2006, 71, 1715-1717. Click here to see article.

Figure

54.  Yian Shi.  "Asymmetric Epoxidation of Olefins by Chiral Ketones", Handbook of Chiral Chemicals”, Ager, D. Ed., CRC Press LLC, Boca Raton, USA, 2006, pp 147-163.

 

53. Christopher P. Burke & Yian Shi.  “Potassium Monoperoxysulfate (first update)”, Electronic Encyclopedia of Reagents for Organic Synthesis 2006.

 

52.  Zackary Crane, David Goeddel, Yonghong Gan, & Yian Shi. "Exploring Structural Effects of Ketone Catalysts on Asymmetric Epoxidation of Olefins", Tetrahedron 2005, 61, 6409-6417. Click here to see article.

 

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51. Jiang Long, Haifeng Du, Kai Li, & Yian Shi. "Catalytic Asymmetric Simmons-Smith Cyclopropanation of Unfunctionalized olefins", Tetrahedron Lett. 2005, 46, 2737-2740. Click here to see article.

 

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50.  Jon C. Lorenz, Michael Frohn, Xiaoming Zhou, Jian-Rong Zhang, Yong Tang, Christopher P. Burke, & Yian Shi. "Transition State Studies on the Dioxirane-Mediated Asymmetric Epoxidation via Kinetic Resolution and Desymmetrization", J. Org. Chem. 2005, 70, 2904-2911. Click here to see article.

 

Figure

 

49.  Yian Shi. "Organocatalytic Oxidation. Ketone-catalyzed Asymmetric Epoxidation of Olefins", Modern Oxidation Methods, Backvall, J.E. Ed., WILEY- VCH, Germany, 2004, pp 51-82.

 

48.  Yian Shi. "Organocatalytic Asymmetric Epoxidation of Olefins by Chiral Ketones", Acc. Chem. Res. 2004, 37, 488-496. Click here to see article.

 

47.  Lianhe Shu & Yian Shi. "Asymmetric Epoxidation cis-ß-Methylstyrenes Catalyzed by N-aryl Substituted Oxazolidinone-containing Ketones. A Beneficial Substituent Effect", Tetrahedron Lett. 2004, 45, 8115-8117. Click here to see article.

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46.  Matthew Hickey, David Goeddel, Zackary Crane, & Yian Shi. "Highly enantioselective epoxidation of styrenes: implication of an electronic effect on the competition between spiro and planar transition states", Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 5794-5798. Click here to see article.

 

45.  Jon C. Lorenz, Jiang Long, Zhiqiang Yang, Song Xue, Yinong Xie, & Yian Shi. "A Novel Class of Tunable Zinc Reagents (RXZnCH2Y) for Efficient Cyclopropanation of Olefins", J. Org. Chem. 2004, 69, 327-334. Click here to see article.

 

Figure

 

44.  Jiang Long, Yi Yuan, & Yian Shi. "Asymmetric Simmons-Smith Cyclopropanation of Unfunctionalized Olefins", J. Am. Chem. Soc. 2003, 125, 13632-13633. Click here to see article.

 

Figure

 

43.   Lianhe Shu, Yu-Mei Shen, Christopher Burke, David Goeddel, & Yian Shi. "An Improved Synthesis of a Ketone Catalyst for Asymmetric Epoxidation of Olefins", J. Org. Chem. 2003, 68, 4963-4965. Click here to see article.

Figure

 

42.   Lianhe Shu, Pingzhen Wang, Yonghong Gan, & Yian Shi. "Asymmetric Epoxidation Catalyzed by N-Aryl-Substituted Oxazolidinone-Containing Ketones: Further Evidence for Electronic Effects", Org. Lett. 2003, 5, 293-296. Click here to see article.

Figure

 

41.  Zhi-Xian Wang, Lianhe Shu, Michael Frohn, Yong Tu, & Yian Shi.  "Asymmetric Epoxidation of trans-ß-Methylstyrene and 1-Phenylcyclohexene Using a D-Fructose-Derived Ketone", Org. Synth. 2003, 80, 9-17. Click here to see article.

 

40.  Yong Tu, Michael Frohn, Zhi-Xian Wang, & Yian Shi.  "Synthesis of 1,2:4,5-Di-O-Isopropylidene-D-Erythro-2,3-Hexodiulo-2,6-Pyranose.  A Highly Enantioselective Ketone Catalyst for Epoxidation", Org. Synth. 2003, 80, 1-8. Click here to see article.

 

39.  Xin-Yan Wu, Xuegong She, & Yian Shi. "Highly Enantioselective Epoxidation of α, ß-Unsaturated Esters by Chiral Dioxirane", J. Am. Chem. Soc., 2002, 124, 8792-8793. Click here to see article.

 

Figure

 

38.  Xiaoming Feng, Lianhe Shu, & Yian Shi. "Chiral Lewis Acid-Catalyzed Resolution of Racemic Enol Ester Epoxides. Conversion of Both Enantiomers of an Enol Ester Epoxide to the Same Enantiomer of Acyloxy Ketone", J. Org. Chem. 2002, 67, 2831-2836. Click here to see article.

 

Figure

 

37. Hongqi Tian, Xuegong She, Hongwu Yu, Lianhe Shu, & Yian Shi. "Designing New Chiral Ketone Catalysts. Asymmetric Epoxidation of cis-Olefins and Terminal Olefins", J. Org. Chem. 2002, 67, 2435-2446. Click here to see article.

Figure

 

36.  Yian Shi. "Organo-Catalysis: Developing Ketone Catalysts for Asymmetric Epoxidation of Olefins", J. Synth. Org. Chem. Jpn 2002, 60, 342-349.

 

35.  Hongqi Tian, Xuegong She, Jiaxi Xu, & Yian Shi. "Enantioselective Epoxidation of Terminal Olefins by Chiral Dioxirane," Org. Lett. 2001, 3, 1929-1931. Click here to see article.

Figure

 

34.  Lianhe Shu & Yian Shi. "An Efficient Ketone Catalyzed Asymmetric Epoxidation Using Hydrogen Peroxide (H2O2) as Primary Oxidant," Tetrahedron 2001, 57, 5213-5218. Click here to see article.

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33.  Hongqi Tian, Xuegong She, & Yian Shi. "Electronic Probing of Ketone Catalysts for Asymmetric Epoxidation. Search for More Robust Catalysts," Org. Lett. 2001, 3, 715-718. Click here to see article.

Figure

 

32.  Yuanming Zhu, Lianhe Shu, Yong Tu, & Yian Shi. "Enantioselective Synthesis and Stereoselective Rearrangements of Enol Ester Epoxides." J. Org. Chem. 2001, 66, 1818-1826. Click here to see article.

 

Figure

 

31.  Zhi-Xian Wang, Susie M. Miller, Oren P. Anderson, & Yian Shi. "Asymmetric Epoxidation by Chiral Ketones Derived From Carbocyclic Analogues of Fructose," J. Org. Chem. 2001, 66, 521-530. Click here to see article.

Figure

 

30.  Michael Frohn & Yian Shi. "Chiral Ketone-Catalyzed Asymmetric Epoxidation of Olefins," Synthesis 2000, 1979-2000. Click here to see article.

 

29.  Hongqi Tian, Xuegong She, Lianhe Shu, Hongwu Yu, & Yian Shi. "Highly Enantioselective Epoxidation of cis-Olefins by Chiral Dioxirane," J. Am. Chem. Soc. 2000, 122, 11551-11552. Click here to see article.

 

28.  Lianhe Shu & Yian Shi. "An Efficient Ketone-Catalyzed Epoxidation Using Hydrogen Peroxide (H2O2) as Oxidant," J. Org. Chem. 2000, 65, 8807-8810. Click here to see article.

 

Figure

 

27.  Xiaoming Feng, Lianhe Shu, & Yian Shi. "Complete Conversion of Racemic Enol Ester Epoxides into Optically Active α-Acyloxy Ketones," J. Am. Chem. Soc. 1999, 121, 11002-11003. Click here to see article.

 

 

26.  Lianhe Shu & Yian Shi. "Asymmetric Epoxidation Using Hydrogen Peroxide (H2O2) as Primary Oxidant," Tetrahedron Lett. 1999, 40, 8721-8724. Click here to see article.

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25.  J. David Warren & Yian Shi. "Chiral Ketone-Catalyzed Asymmetric Epoxidation of 2,2-Disubstituted Vinylsilanes," J. Org. Chem. 1999, 64, 7675-7677. Click here to see article.

 

Figure

 

24.  Zhi-Xian Wang, Guo-An Cao, & Yian Shi. "Chiral Ketone Catalyzed Highly Chemo- and Enantioselective Epoxidation of Conjugated Enynes," J. Org. Chem. 1999, 64, 7646-7650. Click here to see article.

Figure

 

23.  Michael Frohn, Xiaoming Zhou, Jian-Rong Zhang, Yong Tang, & Yian Shi. "Kinetic Resolution of Racemic Cyclic Olefins via Chiral Dioxiranes," J. Am. Chem. Soc. 1999, 121, 7718-7719. Click here to see article.

 

 

22.  Zhi-Xian Wang, Susie M. Miller, Oren P. Anderson, & Yian Shi. "A Class of C2 and Pseudo C2 Symmetric Ketone Catalysts for Asymmetric Epoxidation. Conformational Effect on Catalysis," J. Org. Chem. 1999, 64, 6443-6458. Click here to see article.

 

Figure

 

21. Yuanming Zhu, Karl J. Manske, & Yian Shi. "Dual Mechanisms of Acid-Catalyzed Rearrangement of Enol Ester Epoxides: Enantioselective Formation of α-Acyloxy Ketones," J. Am. Chem. Soc. 1999, 121, 4080-4081. Click here to see article.

 

 

20. Yong Tu, Zhi-Xian Wang, Michael Frohn, Mingqi He, Hongwu Yu, Yong Tang, & Yian Shi. "Structural Probing of Ketone Catalysts for Asymmetric Epoxidation," J. Org. Chem. 1998, 63, 8475-8485. Click here to see article.

 

Figure

 

19. Zhiqiang Yang, Jon C. Lorenz, & Yian Shi. "Exploring New Reactive Species for Cyclopropanation," Tetrahedron Lett. 1998, 39, 8621-8624. Click here to see article.

 

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18. Yuanming Zhu, Yong Tu, Hongwu Yu, & Yian Shi. "Highly Enantioselective Epoxidation of Enol Silyl Ethers and Esters," Tetrahedron Lett. 1998, 39, 7819-7822. Click here to see article.

 

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17.  Michael Frohn, Zhi-Xian Wang, & Yian Shi. "A Mild and Efficient Epoxidation of Olefins Using in situ Generated Dimethyldioxirane at High pH," J. Org. Chem. 1998, 63, 6425-6426. Click here to see article.

 

Figure

 

16.  Guo-An Cao, Zhi-Xian Wang, Yong Tu, & Yian Shi. "Chemo- and Enantioselective Epoxidation of Enynes," Tetrahedron Lett. 1998, 39, 4425-4428. Click here to see article.

 

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15.  Zhi-Xian Wang & Yian Shi. "A pH Study on the Chiral Ketone Catalyzed Asymmetric Epoxidation of Hydroxyalkenes," J. Org. Chem. 1998, 63, 3099-3104. Click here to see article.

 

14.  Michael Frohn, Molly Dalkiewicz, Yong Tu, Zhi-Xian Wang, & Yian Shi. "Highly Regio- and Enantioselective Monoepoxidation of Conjugated Dienes," J. Org. Chem. 1998, 63, 2948-2953. Click here to see article.

 

13.  Zhi-Xian Wang & Yian Shi. "A New Type of Ketone Catalyst for Asymmetric Epoxidation," J. Org. Chem. 1997, 62, 8622-8623. Click here to see article.

 

 

12.  Zhi-Xian Wang, Yong Tu, Michael Frohn, Jian-Rong Zhang, & Yian Shi. "An Efficient Catalytic Asymmetric Epoxidation Method," J. Am. Chem. Soc. 1997, 119, 11224-11235. Click here to see article.

 

 

11.  Zhi-Xian Wang, Yong Tu, Michael Frohn, & Yian Shi. "A Dramatic pH Effect Leads to a Catalytic Asymmetric Epoxidation," J. Org. Chem. 1997, 62, 2328-2329. Click here to see article.

 

Figure

 

10.  Yong Tu, Zhi-Xian Wang, & Yian Shi. "An Efficient Asymmetric Epoxidation Method for trans-Olefins Mediated by a Fructose-Derived Ketone," J. Am. Chem. Soc. 1996, 118, 9806-9807. Click here to see article.

 

 

9.    Chang Fan, Paul C. Moews, Yian Shi, Christopher T. Walsh, & James R. Knox. "A Common Fold for Peptide Synthetases Cleaving ATP to ADP: Glutathione Synthetase and D-Alanine:D-Alanine Ligase of Escherichia coli," Proc. Natl. Acad. Sci. USA 1995, 92, 1172-1176.

8.    Yian Shi & Christopher T. Walsh. "Active Site Mapping of Escherichia coli D-Ala-D-Ala Ligase by Structure-Based Mutagenesis," Biochemistry 1995, 34, 2768-2776.

7.    Yian Shi, Eric D. Brown, & Christopher T. Walsh. "Expression of Recombinant Human Casein Kinase II and Recombinant Heat Shock Protein 90 in Escherichia coli and Characterization of Their Interactions," Proc. Natl. Acad. Sci. USA 1994, 91, 2767-2771.

6.    Jasna Fejzo, Felicia A. Etzkorn, Robert T. Clubb, Yian Shi, Christopher T. Walsh, & Gerhard Wagner. "The Mutant Escherichia coli F112W Cyclophilin Binds Cyclosporin A in Nearly Identical Conformation as Human Cyclophilin," Biochemistry 1994, 33, 5711-5720.

Barry M. Trost & Yian Shi. "Diastereoselective Cycloisomerizations of Enediynes via Palladium Catalysis," J. Am. Chem. Soc. 1993, 115, 12491-12509.

4.    Barry M. Trost & Yian Shi. "Palladium-Catalyzed Cyclizations of Polyenynes. A Palladium Zipper," J. Am. Chem. Soc. 1993, 115, 9421-9438.

3.    Barry M. Trost & Yian Shi. "Cycloisomerization for Atom Economy. Polycycle Construction via Tandem Transition Metal Catalyzed Electrocyclic Processes," J. Am. Chem. Soc. 1992, 114, 791-792.

2.    Barry M. Trost & Yian Shi. "A Pd-Catalyzed Zipper Reaction," J. Am. Chem. Soc. 1991, 113, 701-703.

1.  Ian W. J. Still & Yian Shi. "A Stereoselective Synthesis of Clavularin A from 2-Cycloheptenone," Tetrahedron Lett. 1987, 28, 2489-2490.

 

 

 

 

 

 

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